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Silencing of ETS1 reverses adriamycin resistance in MCF-7/ADR cells via downregulation of MDR1
BACKGROUND: Clinical resistance to chemotherapeutic agents is one of the major hindrances in the treatment of human cancers. Erythroblastosis virus E26 oncogene homolog 1 (ETS1) is involved in the drug resistance of various cancer cells, and is overexpressed in drug-resistant human breast cancer cel...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3995875/ https://www.ncbi.nlm.nih.gov/pubmed/24602286 http://dx.doi.org/10.1186/1475-2867-14-22 |