Cargando…

Activation of Silenced Cytokine Gene Promoters by the Synergistic Effect of TBP-TALE and VP64-TALE Activators

Recent work has shown that the combinatorial use of multiple TALE activators can selectively activate certain cellular genes in inaccessible chromatin regions. In this study, we aimed to interrogate the activation potential of TALEs upon transcriptionally silenced immune genes in the context of non-...

Descripción completa

Detalles Bibliográficos
Autores principales: Anthony, Kim, More, Abhijit, Zhang, Xiaoliu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3995891/
https://www.ncbi.nlm.nih.gov/pubmed/24755922
http://dx.doi.org/10.1371/journal.pone.0095790