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Tripartite Motif-Containing Protein 30 Modulates TCR-Activated Proliferation and Effector Functions in CD4(+) T Cells

To avoid excessive activation, immune signals are tightly controlled by diverse inhibitory proteins. TRIM30, a tripartite motif (TRIM)-containing protein is one of such inhibitors known to function in macrophages. To define the roles of TRIM30, we generated Trim30 knockout (Trim30 (−/−)) mice. Trim3...

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Detalles Bibliográficos
Autores principales: Choi, Un Yung, Hur, Ji Yeon, Lee, Myeong Sup, Zhang, Quanri, Choi, Won Young, Kim, Lark Kyun, Lee, Wook-Bin, Oh, Goo Taeg, Kim, Young-Joon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3995923/
https://www.ncbi.nlm.nih.gov/pubmed/24756037
http://dx.doi.org/10.1371/journal.pone.0095805