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A Novel Genetic Score Approach Using Instruments to Investigate Interactions between Pathways and Environment: Application to Air Pollution

Air pollution has been associated with increased systemic inflammation markers. We developed a new pathway analysis approach to investigate whether gene variants within relevant pathways (oxidative stress, endothelial function, and metal processing) modified the association between particulate air p...

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Detalles Bibliográficos
Autores principales: Bind, Marie-Abele, Coull, Brent, Suh, Helen, Wright, Robert, Baccarelli, Andrea, Vokonas, Pantel, Schwartz, Joel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3995963/
https://www.ncbi.nlm.nih.gov/pubmed/24755831
http://dx.doi.org/10.1371/journal.pone.0096000