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A Novel Genetic Score Approach Using Instruments to Investigate Interactions between Pathways and Environment: Application to Air Pollution
Air pollution has been associated with increased systemic inflammation markers. We developed a new pathway analysis approach to investigate whether gene variants within relevant pathways (oxidative stress, endothelial function, and metal processing) modified the association between particulate air p...
Autores principales: | Bind, Marie-Abele, Coull, Brent, Suh, Helen, Wright, Robert, Baccarelli, Andrea, Vokonas, Pantel, Schwartz, Joel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3995963/ https://www.ncbi.nlm.nih.gov/pubmed/24755831 http://dx.doi.org/10.1371/journal.pone.0096000 |
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