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Impact of Metformin on Endothelial Ischemia-Reperfusion Injury in Humans In Vivo: A Prospective Randomized Open, Blinded-Endpoint Study

INTRODUCTION: Large prospective studies in patients with type 2 diabetes mellitus have demonstrated that metformin treatment improves cardiovascular prognosis, independent of glycemic control. Administration of metformin potently limits infarct size in murine models of myocardial infarction. This st...

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Detalles Bibliográficos
Autores principales: El Messaoudi, Saloua, Schreuder, Tim H., Kengen, Roel D., Rongen, Gerard A., van den Broek, Petra H., Thijssen, Dick H. J., Riksen, Niels P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3996005/
https://www.ncbi.nlm.nih.gov/pubmed/24755906
http://dx.doi.org/10.1371/journal.pone.0096062