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Impact of Metformin on Endothelial Ischemia-Reperfusion Injury in Humans In Vivo: A Prospective Randomized Open, Blinded-Endpoint Study
INTRODUCTION: Large prospective studies in patients with type 2 diabetes mellitus have demonstrated that metformin treatment improves cardiovascular prognosis, independent of glycemic control. Administration of metformin potently limits infarct size in murine models of myocardial infarction. This st...
Autores principales: | El Messaoudi, Saloua, Schreuder, Tim H., Kengen, Roel D., Rongen, Gerard A., van den Broek, Petra H., Thijssen, Dick H. J., Riksen, Niels P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3996005/ https://www.ncbi.nlm.nih.gov/pubmed/24755906 http://dx.doi.org/10.1371/journal.pone.0096062 |
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