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Chemokine receptor CCR6 expression is regulated by miR-518a-5p in colorectal cancer cells

BACKGROUND: Recently, involvement of the chemokine/receptor system CCL20/CCR6 in colorectal cancer (CRC) progression was shown. Here, we analyzed the functional interaction of miRNA-518-5p (miR-518a-5p) with CCR6 and its impact on CCR6 expression in CRC cells. METHODS: MiR-518a-5p was identified by...

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Detalles Bibliográficos
Autores principales: Rubie, Claudia, Kruse, Bianca, Frick, Vilma Oliveira, Kölsch, Kathrin, Ghadjar, Pirus, Wagner, Mathias, Grässer, Friedrich, Wagenpfeil, Stefan, Glanemann, Mathias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3996063/
https://www.ncbi.nlm.nih.gov/pubmed/24559209
http://dx.doi.org/10.1186/1479-5876-12-48