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Host bone marrow-derived IL-12 enhances donor T cell engraftment in a mouse model of bone marrow transplantation

BACKGROUND: Donor cell engraftment is critical for the success of allogeneic bone marrow transplants. Graft failure is a result of donor cells either failing to engraft initially or being eliminated at later time points. Donor cell engraftment is facilitated by donor T cells, which eliminate residua...

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Detalles Bibliográficos
Autores principales: Darlak, Katarzyna A, Wang, Ying, Li, Jian-Ming, Harris, Wayne AC, Giver, Cynthia R, Huang, Chunzi, Waller, Edmund K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3996069/
https://www.ncbi.nlm.nih.gov/pubmed/24580829
http://dx.doi.org/10.1186/1756-8722-7-16