Dovitinib synergizes with oxaliplatin in suppressing cell proliferation and inducing apoptosis in colorectal cancer cells regardless of RAS-RAF mutation status

BACKGROUND: Cancer is the result of a multistep process of genomic alterations, including mutations in key regulatory proteins that result in loss of balanced gene expression and subsequent malignant transformation. Throughout the various stages of colorectal carcinoma (CRC), complex genetic alterat...

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Detalles Bibliográficos
Autores principales: Gaur, Shikha, Chen, Linling, Ann, Vincent, Lin, Wei-Chen, Wang, Yafan, Chang, Vincent HS, Hsu, Nan Yong, Shia, Her-Shuyong, Yen, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3996163/
https://www.ncbi.nlm.nih.gov/pubmed/24495750
http://dx.doi.org/10.1186/1476-4598-13-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3996163/
https://www.ncbi.nlm.nih.gov/pubmed/24495750
http://dx.doi.org/10.1186/1476-4598-13-21

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