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Metronomic oral paclitaxel shows anti-tumor effects in an orthotopic mouse model of ovarian cancer

OBJECTIVE: The purpose of this study was to compare the in vivo anti-tumor efficacy of a mucoadhesive, lipid-based, oral paclitaxel formulation (DHP107) with traditional, intraperitoneal (IP) paclitaxel using an orthotopic mouse model of chemotherapy-sensitive SKOV3ip1 ovarian cancer. METHODS: To de...

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Detalles Bibliográficos
Autores principales: Hahn, Ho-Suap, Lee, Ki-Heon, Lee, In-Ho, Lee, Jae-Ho, Whang, Chang-Sung, Jo, Yeong-Woo, Kim, Tae-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Asian Society of Gynecologic Oncology; Korean Society of Gynecologic Oncology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3996263/
https://www.ncbi.nlm.nih.gov/pubmed/24761217
http://dx.doi.org/10.3802/jgo.2014.25.2.130