Neutrophil Cathepsin G, but Not Elastase, Induces Aggregation of MCF-7 Mammary Carcinoma Cells by a Protease Activity-Dependent Cell-Oriented Mechanism

We previously found that a neutrophil serine protease, cathepsin G, weakens adherence to culture substrates and induces E-cadherin-dependent aggregation of MCF-7 human breast cancer cells through its protease activity. In this study, we examined whether aggregation is caused by degradation of adhesi...

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Detalles Bibliográficos
Autores principales: Yui, Satoru, Osawa, Yuuki, Ichisugi, Takeo, Morimoto-Kamata, Riyo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3996324/
https://www.ncbi.nlm.nih.gov/pubmed/24803743
http://dx.doi.org/10.1155/2014/971409

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3996324/
https://www.ncbi.nlm.nih.gov/pubmed/24803743
http://dx.doi.org/10.1155/2014/971409

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