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Neutrophil Cathepsin G, but Not Elastase, Induces Aggregation of MCF-7 Mammary Carcinoma Cells by a Protease Activity-Dependent Cell-Oriented Mechanism
We previously found that a neutrophil serine protease, cathepsin G, weakens adherence to culture substrates and induces E-cadherin-dependent aggregation of MCF-7 human breast cancer cells through its protease activity. In this study, we examined whether aggregation is caused by degradation of adhesi...
Autores principales: | Yui, Satoru, Osawa, Yuuki, Ichisugi, Takeo, Morimoto-Kamata, Riyo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3996324/ https://www.ncbi.nlm.nih.gov/pubmed/24803743 http://dx.doi.org/10.1155/2014/971409 |
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