Peroxisome Proliferator Activator Receptor (PPAR)-γ Ligand, but Not PPAR-α, Ameliorates Cyclophosphamide-Induced Oxidative Stress and Inflammation in Rat Liver

Hepatoprotective potential of peroxisome proliferator activator receptor (PPAR)-α and -γ agonists, fenofibrate (FEN), and pioglitazone (PIO), respectively, against cyclophosphamide (CP)-induced toxicity has been investigated in rat. FEN and PIO (150 and 10 mg/kg/day, resp.) were given orally for 4 w...

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Detalles Bibliográficos
Autores principales: El-Sheikh, Azza A. K., Rifaai, Rehab A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3996363/
https://www.ncbi.nlm.nih.gov/pubmed/24803924
http://dx.doi.org/10.1155/2014/626319

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3996363/
https://www.ncbi.nlm.nih.gov/pubmed/24803924
http://dx.doi.org/10.1155/2014/626319

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