Combination of Complement-Dependent Cytotoxicity and Relative Fluorescent Quantification of HLA Length Polymorphisms Facilitates the Detection of a Loss of Heterozygosity

Loss of heterozygosity (LOH) is a common event in malignant cells. In this work we introduce a new approach to identify patients with loss of heterozygosity in the HLA region either at first diagnosis or after HLA mismatched allogeneic HSCT. Diagnosis of LOH requires a high purity of recipient targe...

Descripción completa

Detalles Bibliográficos
Autores principales: Witter, Klaus, Reibke, Roland, Subklewe, Marion, Zahn, Robert, Kauke, Teresa, Spiekermann, Karsten, Spannagl, Michael, Tischer, Johanna, Hiddemann, Wolfgang, Dick, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3996364/
https://www.ncbi.nlm.nih.gov/pubmed/24860670
http://dx.doi.org/10.1155/2014/541345

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3996364/
https://www.ncbi.nlm.nih.gov/pubmed/24860670
http://dx.doi.org/10.1155/2014/541345

Ejemplares similares