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Profiling of drugs and environmental chemicals for functional impairment of neural crest migration in a novel stem cell-based test battery

Developmental toxicity in vitro assays have hitherto been established as stand-alone systems, based on a limited number of toxicants. Within the embryonic stem cell-based novel alternative tests project, we developed a test battery framework that allows inclusion of any developmental toxicity assay...

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Detalles Bibliográficos
Autores principales: Zimmer, B., Pallocca, G., Dreser, N., Foerster, S., Waldmann, T., Westerhout, J., Julien, S., Krause, K. H., van Thriel, C., Hengstler, J. G., Sachinidis, A., Bosgra, S., Leist, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3996367/
https://www.ncbi.nlm.nih.gov/pubmed/24691702
http://dx.doi.org/10.1007/s00204-014-1231-9