Apoptosis Therapy in Cancer: The First Single-molecule Co-activating p53 and the Translocator Protein in Glioblastoma

In the complex scenario of cancer, treatment with compounds targeting multiple cell pathways has been emerging. In Glioblastoma Multiforme (GBM), p53 and Translocator Protein (TSPO), both acting as apoptosis inducers, represent two attractive intracellular targets. On this basis, novel indolylglyoxy...

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Detalles Bibliográficos
Autores principales: Daniele, Simona, Taliani, Sabrina, Da Pozzo, Eleonora, Giacomelli, Chiara, Costa, Barbara, Trincavelli, Maria Letizia, Rossi, Leonardo, La Pietra, Valeria, Barresi, Elisabetta, Carotenuto, Alfonso, Limatola, Antonio, Lamberti, Anna, Marinelli, Luciana, Novellino, Ettore, Da Settimo, Federico, Martini, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3996484/
https://www.ncbi.nlm.nih.gov/pubmed/24756113
http://dx.doi.org/10.1038/srep04749

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3996484/
https://www.ncbi.nlm.nih.gov/pubmed/24756113
http://dx.doi.org/10.1038/srep04749

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