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Apoptosis Therapy in Cancer: The First Single-molecule Co-activating p53 and the Translocator Protein in Glioblastoma
In the complex scenario of cancer, treatment with compounds targeting multiple cell pathways has been emerging. In Glioblastoma Multiforme (GBM), p53 and Translocator Protein (TSPO), both acting as apoptosis inducers, represent two attractive intracellular targets. On this basis, novel indolylglyoxy...
Autores principales: | Daniele, Simona, Taliani, Sabrina, Da Pozzo, Eleonora, Giacomelli, Chiara, Costa, Barbara, Trincavelli, Maria Letizia, Rossi, Leonardo, La Pietra, Valeria, Barresi, Elisabetta, Carotenuto, Alfonso, Limatola, Antonio, Lamberti, Anna, Marinelli, Luciana, Novellino, Ettore, Da Settimo, Federico, Martini, Claudia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3996484/ https://www.ncbi.nlm.nih.gov/pubmed/24756113 http://dx.doi.org/10.1038/srep04749 |
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