LPHN3, a presynaptic adhesion-GPCR implicated in ADHD, regulates the strength of neocortical layer 2/3 synaptic input to layer 5

BACKGROUND: Latrophilins (LPHNs) are a small family of neuronal adhesion-GPCRs originally discovered as receptors for the black widow spider toxin α-latrotoxin. Mutations in LPHN3 have recently been identified as risk factors for attention deficit hyperactivity disorder (ADHD) in humans, but their p...

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Detalles Bibliográficos
Autores principales: O’Sullivan, Matthew L, Martini, Francesca, von Daake, Sventja, Comoletti, Davide, Ghosh, Anirvan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3996519/
https://www.ncbi.nlm.nih.gov/pubmed/24739570
http://dx.doi.org/10.1186/1749-8104-9-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3996519/
https://www.ncbi.nlm.nih.gov/pubmed/24739570
http://dx.doi.org/10.1186/1749-8104-9-7

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