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Impact of genomic polymorphisms on the repertoire of human MHC class I-associated peptides

For decades, the global impact of genomic polymorphisms on the repertoire of peptides presented by major histocompatibility complex (MHC) has remained a matter of speculation. Here we present a novel approach that enables high-throughput discovery of polymorphic MHC class I-associated peptides (MIPs...

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Detalles Bibliográficos
Autores principales: Granados, Diana Paola, Sriranganadane, Dev, Daouda, Tariq, Zieger, Antoine, Laumont, Céline M., Caron-Lizotte, Olivier, Boucher, Geneviève, Hardy, Marie-Pierre, Gendron, Patrick, Côté, Caroline, Lemieux, Sébastien, Thibault, Pierre, Perreault, Claude
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3996541/
https://www.ncbi.nlm.nih.gov/pubmed/24714562
http://dx.doi.org/10.1038/ncomms4600