The glucosaminidase domain of Atl – the major Staphylococcus aureus autolysin – has DNA-binding activity

In this communication, we describe evidence demonstrating the capacity of Atl, the major Staphylococcus aureus autolytic enzyme to bind DNA. Electrophoretic mobility shift assays (EMSA) show that both the Atl protein and the endo-β-N-acetylglucosaminidase (GL) domain were able to bind DNA of nonspec...

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Detalles Bibliográficos
Autores principales: Grilo, Inês R, Ludovice, Ana Madalena, Tomasz, Alexander, de Lencastre, Hermínia, Sobral, Rita G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Ltd. 2014
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3996572/
https://www.ncbi.nlm.nih.gov/pubmed/24585695
http://dx.doi.org/10.1002/mbo3.165

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3996572/
https://www.ncbi.nlm.nih.gov/pubmed/24585695
http://dx.doi.org/10.1002/mbo3.165

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