A Polymorphism in the IL-5 Gene is Associated with Inhibitor Development in Severe Hemophilia A Patients

Objective: A severe complication in the replacement therapy of hemophilia A (HA) patients is the development of alloantibodies (inhibitors) against factor VIII, which neutralizes the substituted factor. The primary genetic risk factors influencing the development of inhibitors are F8 gene mutations....

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Detalles Bibliográficos
Autores principales: Fidancı, İnanç Değer, Zülfikar, Bülent, Kavaklı, Kaan, Ar, M. Cem, Kılınç, Yurdanur, Başlar, Zafer, Çağlayan, Server Hande
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Galenos Publishing 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3996645/
https://www.ncbi.nlm.nih.gov/pubmed/24764725
http://dx.doi.org/10.4274/Tjh.2012.0197

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3996645/
https://www.ncbi.nlm.nih.gov/pubmed/24764725
http://dx.doi.org/10.4274/Tjh.2012.0197

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