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Sensory-Driven Enhancement of Calcium Signals in Individual Purkinje Cell Dendrites of Awake Mice

Climbing fibers (CFs) are thought to contribute to cerebellar plasticity and learning by triggering a large influx of dendritic calcium in the postsynaptic Purkinje cell (PC) to signal the occurrence of an unexpected sensory event. However, CFs fire about once per second whether or not an event occu...

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Detalles Bibliográficos
Autores principales: Najafi, Farzaneh, Giovannucci, Andrea, Wang, Samuel S.-H., Medina, Javier F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3996650/
https://www.ncbi.nlm.nih.gov/pubmed/24582958
http://dx.doi.org/10.1016/j.celrep.2014.02.001