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Frequent L1 retrotranspositions originating from TTC28 in colorectal cancer

L1 element retrotranspositions have been found to alter expression of genes neighboring the insertion sites, potentially involving them in tumorigenesis and tumor progression. In colorectal cancer (CRC), L1 insertions have been found to target genes with a role in tumorigenesis. Structural changes s...

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Detalles Bibliográficos
Autores principales: Pitkänen, Esa, Cajuso, Tatiana, Katainen, Riku, Kaasinen, Eevi, Välimäki, Niko, Palin, Kimmo, Taipale, Jussi, Aaltonen, Lauri A., Kilpivaara, Outi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3996660/
https://www.ncbi.nlm.nih.gov/pubmed/24553397