Targeting Src-mediated Tyr216 phosphorylation and activation of GSK-3 in prostate cancer cells inhibit prostate cancer progression in vitro and in vivo

Recent studies suggest a positive correlation between glycogen synthase kinase-3 (GSK-3) activation and tumor growth. Currently, it is unclear how both Akt that inhibits GSK-3 and active GSK-3 are maintained concurrently in tumor cells. We investigated the role of GSK-3 and the existence of an Akt-r...

Descripción completa

Detalles Bibliográficos
Autores principales: Goc, Anna, Al-Husein, Belal, Katsanevas, Katerina, Steinbach, Alison, Lou, Uvette, Sabbineni, Harika, DeRemer, David L., Somanath, Payaningal R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3996673/
https://www.ncbi.nlm.nih.gov/pubmed/24519956

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3996673/
https://www.ncbi.nlm.nih.gov/pubmed/24519956

Ejemplares similares