Cargando…

Enhanced hypoglycemic effect of biotin-modified liposomes loading insulin: effect of formulation variables, intracellular trafficking, and cytotoxicity

Peroral protein/peptide delivery has been one of the most challenging, but encouraging topics in pharmaceutics. This article was intended to explore the potential of biotin-modified liposomes (BLPs) as oral insulin delivery carriers. By incorporating biotin-DSPE into the lipid bilayer, we prepared B...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Xingwang, Qi, Jianping, Lu, Yi, Hu, Xiongwei, He, Wei, Wu, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer 2014
Materias:	Nano Express
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3996857/ https://www.ncbi.nlm.nih.gov/pubmed/24739082 http://dx.doi.org/10.1186/1556-276X-9-185

Ejemplares similares

Effects of Micro-environmental pH of Liposome on Chemical Stability of Loaded Drug
por: Shao, Xiao-Ru, et al.
Publicado: (2017)

Formulation and Drug Loading Features of Nano-Erythrocytes
por: Dong, Xiaoting, et al.
Publicado: (2017)

Bufalin-Loaded PEGylated Liposomes: Antitumor Efficacy, Acute Toxicity, and Tissue Distribution
por: Yuan, Jiani, et al.
Publicado: (2019)

Hydrophobic Drug-Loaded PEGylated Magnetic Liposomes for Drug-Controlled Release
por: Hardiansyah, Andri, et al.
Publicado: (2017)

Novel docetaxel-loaded nanoparticles based on poly(lactide-co-caprolactone) and poly(lactide-co-glycolide-co-caprolactone) for prostate cancer treatment: formulation, characterization, and cytotoxicity studies
por: Sanna, Vanna, et al.
Publicado: (2011)

ICAM-1-Targeted Liposomes Loaded with Liver X Receptor Agonists Suppress PDGF-Induced Proliferation of Vascular Smooth Muscle Cells
por: Huang, Xu, et al.
Publicado: (2017)

Designing Aptamer-Gold Nanoparticle-Loaded pH-Sensitive Liposomes Encapsulate Morin for Treating Cancer
por: Ding, Xiaoyuan, et al.
Publicado: (2020)

Improved Antitumor Efficacy and Pharmacokinetics of Bufalin via PEGylated Liposomes
por: Yuan, Jiani, et al.
Publicado: (2017)

Hydrogels containing redispersible spray-dried melatonin-loaded nanocapsules: a formulation for transdermal-controlled delivery
por: Hoffmeister, Cristiane RD, et al.
Publicado: (2012)

Cytotoxic effects and the mechanism of three types of magnetic nanoparticles on human hepatoma BEL-7402 cells
por: Kai, Wei, et al.
Publicado: (2011)

Preparation and Evaluation of Liposomes Co-Loaded with Doxorubicin, Phospholipase D Inhibitor 5-Fluoro-2-Indolyl Deschlorohalopemide (FIPI) and D-Alpha Tocopheryl Acid Succinate (α-TOS) for Anti-Metastasis
por: Song, Maoyuan, et al.
Publicado: (2019)

Effect of introduction of chondroitin sulfate into polymer-peptide conjugate responding to intracellular signals
por: Tomiyama, Tetsuro, et al.
Publicado: (2011)

Doxorubicin-loaded cholic acid-polyethyleneimine micelles for targeted delivery of antitumor drugs: synthesis, characterization, and evaluation of their in vitro cytotoxicity
por: Amjad, Muhammad Wahab, et al.
Publicado: (2012)

Preparation and Pharmacokinetic Study of Daidzein Long-Circulating Liposomes
por: Wang, Qiao, et al.
Publicado: (2019)

Magnetic liposomes for colorectal cancer cells therapy by high-frequency magnetic field treatment
por: Hardiansyah, Andri, et al.
Publicado: (2014)

The Cost-Effective Preparation of Green Fluorescent Carbon Dots for Bioimaging and Enhanced Intracellular Drug Delivery
por: Sun, Yuqing, et al.
Publicado: (2020)

Effect of surface properties of silica nanoparticles on their cytotoxicity and cellular distribution in murine macrophages
por: Nabeshi, Hiromi, et al.
Publicado: (2011)

Cytotoxic effects of ZnO hierarchical architectures on RSC96 Schwann cells
por: Yin, Yixia, et al.
Publicado: (2012)

Fullerene C(60) Penetration into Leukemic Cells and Its Photoinduced Cytotoxic Effects
por: Franskevych, D., et al.
Publicado: (2017)

Toxicity Assessment of PEG-PCCL Nanoparticles and Preliminary Investigation on Its Anti-tumor Effect of Paclitaxel-Loading
por: Li, Wei, et al.
Publicado: (2018)

Evaluating the Suitability of Using Rat Models for Preclinical Efficacy and Side Effects with Inhaled Corticosteroids Nanosuspension Formulations
por: Chiang, Po-Chang, et al.
Publicado: (2010)

Cytotoxicity Effects of Different Surfactant Molecules Conjugated to Carbon Nanotubes on Human Astrocytoma Cells
por: Dong, Lifeng, et al.
Publicado: (2009)

Antimicrobial and Cytotoxicity Effects of Synthesized Silver Nanoparticles from Punica granatum Peel Extract
por: Devanesan, Sandhanasamy, et al.
Publicado: (2018)

Dual integrin αvβ 3 and NRP-1-Targeting Paramagnetic Liposome for Tumor Early Detection in Magnetic Resonance Imaging
por: Song, Yin, et al.
Publicado: (2018)

Biocompatibility of Liposome Nanocarriers in the Rat Inner Ear After Intratympanic Administration
por: Zou, Jing, et al.
Publicado: (2017)

pH- and acoustic-responsive platforms based on perfluoropentane-loaded protein nanoparticles for ovarian tumor-targeted ultrasound imaging and therapy
por: Li, Jianping, et al.
Publicado: (2020)

Enhanced Bioavailability and Anticancer Effect of Curcumin-Loaded Electrospun Nanofiber: In Vitro and In Vivo Study
por: Wang, Chuan, et al.
Publicado: (2015)

Reduced cytotoxicity of insulin-immobilized CdS quantum dots using PEG as a spacer
por: Selim, KM Kamruzzaman, et al.
Publicado: (2011)

Gd(III)-DOTA-modified sonosensitive liposomes for ultrasound-triggered release and MR imaging
por: Jung, Suk Hyun, et al.
Publicado: (2012)

Enhanced localization of anticancer drug in tumor tissue using polyethylenimine-conjugated cationic liposomes
por: Han, Hee Dong, et al.
Publicado: (2014)

Inhibition of HIV Virus by Neutralizing Vhh Attached to Dual Functional Liposomes Encapsulating Dapivirine
por: Wang, Scarlet Xiaoyan, et al.
Publicado: (2016)

Vertical nanowire probes for intracellular signaling of living cells
por: Lee, Ki-Young, et al.
Publicado: (2014)

One-step synthesis of platinum nanoparticles loaded in alginate bubbles
por: Yang, Chih-Hui, et al.
Publicado: (2014)

Electromagnetic Enhancement of Graphene Raman Spectroscopy by Ordered and Size-Tunable Au Nanostructures
por: Zhang, Shuguang, et al.
Publicado: (2015)

Studies on Preparation of Photosensitizer Loaded Magnetic Silica Nanoparticles and Their Anti-Tumor Effects for Targeting Photodynamic Therapy
por: Chen, Zhi-Long, et al.
Publicado: (2009)

Folate Receptor-targeted Bioflavonoid Genistein-loaded Chitosan Nanoparticles for Enhanced Anticancer Effect in Cervical Cancers
por: Cai, Limei, et al.
Publicado: (2017)

Therapeutic Potential of Delivering Arsenic Trioxide into HPV-Infected Cervical Cancer Cells Using Liposomal Nanotechnology
por: Wang, Xiaoyan, et al.
Publicado: (2016)

Preparation of Glycyrrhetinic Acid Liposomes Using Lyophilization Monophase Solution Method: Preformulation, Optimization, and In Vitro Evaluation
por: Liu, Tingting, et al.
Publicado: (2018)

Effects of multiwalled carbon nanotubes and triclocarban on several eukaryotic cell lines: elucidating cytotoxicity, endocrine disruption, and reactive oxygen species generation
por: Simon, Anne, et al.
Publicado: (2014)

Regulation of Transgene Expression in Tumor Cells by Exploiting Endogenous Intracellular Signals
por: Asai, Daisuke, et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_gd5l74m1iqh8g7davvd8q9kmcn