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Roles of eIF2α kinases in the pathogenesis of Alzheimer’s disease
Cell signaling in response to an array of diverse stress stimuli converges on the phosphorylation of eukaryotic initiation factor-2α (eIF2α). Evidence is accumulating that persistent eIF2α phosphorylation at Ser51 through prolonged overactivation of regulatory kinases occurs in neurodegenerative dis...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3997008/ https://www.ncbi.nlm.nih.gov/pubmed/24795560 http://dx.doi.org/10.3389/fnmol.2014.00022 |