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Roles of eIF2α kinases in the pathogenesis of Alzheimer’s disease

Cell signaling in response to an array of diverse stress stimuli converges on the phosphorylation of eukaryotic initiation factor-2α (eIF2α). Evidence is accumulating that persistent eIF2α phosphorylation at Ser51 through prolonged overactivation of regulatory kinases occurs in neurodegenerative dis...

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Detalles Bibliográficos
Autor principal: Ohno, Masuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3997008/
https://www.ncbi.nlm.nih.gov/pubmed/24795560
http://dx.doi.org/10.3389/fnmol.2014.00022