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Deciphering the Molecular Profile of Plaques, Memory Decline and Neuron Loss in Two Mouse Models for Alzheimer’s Disease by Deep Sequencing

One of the central research questions on the etiology of Alzheimer’s disease (AD) is the elucidation of the molecular signatures triggered by the amyloid cascade of pathological events. Next-generation sequencing allows the identification of genes involved in disease processes in an unbiased manner....

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Detalles Bibliográficos
Autores principales: Bouter, Yvonne, Kacprowski, Tim, Weissmann, Robert, Dietrich, Katharina, Borgers, Henning, Brauß, Andreas, Sperling, Christian, Wirths, Oliver, Albrecht, Mario, Jensen, Lars R., Kuss, Andreas W., Bayer, Thomas A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3997018/
https://www.ncbi.nlm.nih.gov/pubmed/24795628
http://dx.doi.org/10.3389/fnagi.2014.00075