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Deletion of PTEN produces autism-like behavioral deficits and alterations in synaptic proteins

Many genes have been implicated in the underlying cause of autism but each gene accounts for only a small fraction of those diagnosed with autism. There is increasing evidence that activity-dependent changes in neuronal signaling could act as a convergent mechanism for many of the changes in synapti...

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Detalles Bibliográficos
Autores principales: Lugo, Joaquin N., Smith, Gregory D., Arbuckle, Erin P., White, Jessika, Holley, Andrew J., Floruta, Crina M., Ahmed, Nowrin, Gomez, Maribel C., Okonkwo, Obi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3997048/
https://www.ncbi.nlm.nih.gov/pubmed/24795561
http://dx.doi.org/10.3389/fnmol.2014.00027