Silencing miR-21 Sensitizes Non-Small Cell Lung Cancer A549 Cells to Ionizing Radiation through Inhibition of PI3K/Akt

We investigated the role of microRNA-21 (miR-21) in radiotherapy resistance of non-small cell lung cancers (NSCLC) and the underlying molecular mechanism. A549 cells were transfected with anti-miR-21 or the negative control oligonucleotides and real-time PCR was applied to detect miR-21 expression l...

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Detalles Bibliográficos
Autores principales: Ma, Yongfu, Xia, Hui, Liu, Yang, Li, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3997135/
https://www.ncbi.nlm.nih.gov/pubmed/24804226
http://dx.doi.org/10.1155/2014/617868

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3997135/
https://www.ncbi.nlm.nih.gov/pubmed/24804226
http://dx.doi.org/10.1155/2014/617868

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