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Glycogen Synthase Kinase-3 Regulates Production of Amyloid-β Peptides and Tau Phosphorylation in Diabetic Rat Brain

The pathogenesis of diabetic neurological complications is not fully understood. Diabetes mellitus (DM) and Alzheimer's disease (AD) are characterized by amyloid deposits. Glycogen synthase kinase-3 (GSK-3) plays an important role in the pathogenesis of AD and DM. Here we tried to investigate t...

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Detalles Bibliográficos
Autores principales: Qu, Zhong-Sen, Li, Liang, Sun, Xiao-Jiang, Zhao, Yu-Wu, Zhang, Jin, Geng, Zhi, Fu, Jian-Liang, Ren, Qing-Guo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3997149/
https://www.ncbi.nlm.nih.gov/pubmed/24983010
http://dx.doi.org/10.1155/2014/878123