Influence of the length of target DNA overhang proximal to the array surface on discrimination of single-base mismatches on a 25-mer oligonucleotide array

BACKGROUND: The performance of probes on an oligonucleotide microarray can be characterised in terms of hybridisation signal strength and the ability to discriminate sequence mismatches between the probe and the hybridising target strand, such as those resulting from SNPs. Various properties of the...

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Detalles Bibliográficos
Autores principales: Tomlinson, Jenny, Harrison, Catherine, Boonham, Neil, Goodchild, Sarah A, Weller, Simon A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3997201/
https://www.ncbi.nlm.nih.gov/pubmed/24742004
http://dx.doi.org/10.1186/1756-0500-7-251

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3997201/
https://www.ncbi.nlm.nih.gov/pubmed/24742004
http://dx.doi.org/10.1186/1756-0500-7-251

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