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Influence of the length of target DNA overhang proximal to the array surface on discrimination of single-base mismatches on a 25-mer oligonucleotide array
BACKGROUND: The performance of probes on an oligonucleotide microarray can be characterised in terms of hybridisation signal strength and the ability to discriminate sequence mismatches between the probe and the hybridising target strand, such as those resulting from SNPs. Various properties of the...
Autores principales: | Tomlinson, Jenny, Harrison, Catherine, Boonham, Neil, Goodchild, Sarah A, Weller, Simon A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3997201/ https://www.ncbi.nlm.nih.gov/pubmed/24742004 http://dx.doi.org/10.1186/1756-0500-7-251 |
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