Efavirenz Promotes β-Secretase Expression and Increased Aβ(1-40,42) via Oxidative Stress and Reduced Microglial Phagocytosis: Implications for HIV Associated Neurocognitive Disorders (HAND)

Efavirenz (EFV) is among the most commonly used antiretroviral drugs globally, causes neurological symptoms that interfere with adherence and reduce tolerability, and may have central nervous system (CNS) effects that contribute in part to HIV associated neurocognitive disorders (HAND) in patients o...

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Detalles Bibliográficos
Autores principales: Brown, Lecia A. M., Jin, Jingji, Ferrell, Darren, Sadic, Edin, Obregon, Demian, Smith, Adam J., Tan, Jun, Giunta, Brian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3997351/
https://www.ncbi.nlm.nih.gov/pubmed/24759994
http://dx.doi.org/10.1371/journal.pone.0095500

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3997351/
https://www.ncbi.nlm.nih.gov/pubmed/24759994
http://dx.doi.org/10.1371/journal.pone.0095500

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