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A New Polymorphism Biomarker rs629367 Associated with Increased Risk and Poor Survival of Gastric Cancer in Chinese by Up-Regulated miRNA-let-7a Expression

BACKGROUND: Variant in pri-miRNA could affect miRNA expression and mature process or splicing efficiency, thus altering the hereditary susceptibility and prognosis of cancer. We aimed to assess miRNA-let-7 single nucleotide polymorphisms (SNP) associated with the risk and prognosis of gastric cancer...

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Detalles Bibliográficos
Autores principales: Xu, Qian, Dong, Qiguan, He, Caiyun, Liu, Wenjing, Sun, Liping, Liu, Jingwei, Xing, Chengzhong, Li, Xiaohang, Wang, Bengang, Yuan, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3997364/
https://www.ncbi.nlm.nih.gov/pubmed/24760009
http://dx.doi.org/10.1371/journal.pone.0095249