Importance of Gradients in Membrane Properties and Electrical Coupling in Sinoatrial Node Pacing

The sinoatrial node (SAN) is heterogeneous in terms of cell size, ion channels, current densities, connexins and electrical coupling. For example, Na(v)1.5 (responsible for I (Na)) and Cx43 (responsible for electrical coupling) are absent from the centre of the SAN (normally the leading pacemaker si...

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Detalles Bibliográficos
Autores principales: Inada, Shin, Zhang, Henggui, Tellez, James O., Shibata, Nitaro, Nakazawa, Kazuo, Kamiya, Kaichiro, Kodama, Itsuo, Mitsui, Kazuyuki, Dobrzynski, Halina, Boyett, Mark R., Honjo, Haruo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3997424/
https://www.ncbi.nlm.nih.gov/pubmed/24759974
http://dx.doi.org/10.1371/journal.pone.0094565

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3997424/
https://www.ncbi.nlm.nih.gov/pubmed/24759974
http://dx.doi.org/10.1371/journal.pone.0094565

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