Triptolide induces apoptotic cell death of human cholangiocarcinoma cells through inhibition of myeloid cell leukemia-1

BACKGROUND: Cholangiocarcinoma (CCA), a devastating neoplasm, is highly resistant to current chemotherapies. CCA cells frequently overexpress the antiapoptotic protein myeloid cell leukemia-1(Mcl-1), which is responsible for its extraordinary ability to evade cell death. Triptolide, a bioactive ingr...

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Detalles Bibliográficos
Autores principales: Ding, Xiwei, Zhang, Bin, Pei, Qingshan, Pan, Jianmei, Huang, Shuling, Yang, Yan, Zhu, Zhu, Lv, Ying, Zou, Xiaoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3997440/
https://www.ncbi.nlm.nih.gov/pubmed/24742042
http://dx.doi.org/10.1186/1471-2407-14-271

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3997440/
https://www.ncbi.nlm.nih.gov/pubmed/24742042
http://dx.doi.org/10.1186/1471-2407-14-271

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