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Retrotransposon Hypomethylation in Melanoma and Expression of a Placenta-Specific Gene

In the human placenta, DNA hypomethylation permits the expression of retrotransposon-derived genes that are normally silenced by methylation in somatic tissues. We previously identified hypomethylation of a retrotransposon-derived transcript of the voltage-gated potassium channel gene KCNH5 that is...

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Detalles Bibliográficos
Autores principales: Macaulay, Erin C., Roberts, Hester E., Cheng, Xi, Jeffs, Aaron R., Baguley, Bruce C., Morison, Ian M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3997481/
https://www.ncbi.nlm.nih.gov/pubmed/24759919
http://dx.doi.org/10.1371/journal.pone.0095840