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Retrotransposon Hypomethylation in Melanoma and Expression of a Placenta-Specific Gene
In the human placenta, DNA hypomethylation permits the expression of retrotransposon-derived genes that are normally silenced by methylation in somatic tissues. We previously identified hypomethylation of a retrotransposon-derived transcript of the voltage-gated potassium channel gene KCNH5 that is...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3997481/ https://www.ncbi.nlm.nih.gov/pubmed/24759919 http://dx.doi.org/10.1371/journal.pone.0095840 |