Coxsackievirus Cloverleaf RNA Containing a 5′ Triphosphate Triggers an Antiviral Response via RIG-I Activation

Upon viral infections, pattern recognition receptors (PRRs) recognize pathogen-associated molecular patterns (PAMPs) and stimulate an antiviral state associated with the production of type I interferons (IFNs) and inflammatory markers. Type I IFNs play crucial roles in innate antiviral responses by...

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Detalles Bibliográficos
Autores principales: Feng, Qian, Langereis, Martijn A., Olagnier, David, Chiang, Cindy, van de Winkel, Roel, van Essen, Peter, Zoll, Jan, Hiscott, John, van Kuppeveld, Frank J. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3997492/
https://www.ncbi.nlm.nih.gov/pubmed/24759703
http://dx.doi.org/10.1371/journal.pone.0095927

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3997492/
https://www.ncbi.nlm.nih.gov/pubmed/24759703
http://dx.doi.org/10.1371/journal.pone.0095927

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