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Coxsackievirus Cloverleaf RNA Containing a 5′ Triphosphate Triggers an Antiviral Response via RIG-I Activation
Upon viral infections, pattern recognition receptors (PRRs) recognize pathogen-associated molecular patterns (PAMPs) and stimulate an antiviral state associated with the production of type I interferons (IFNs) and inflammatory markers. Type I IFNs play crucial roles in innate antiviral responses by...
Autores principales: | Feng, Qian, Langereis, Martijn A., Olagnier, David, Chiang, Cindy, van de Winkel, Roel, van Essen, Peter, Zoll, Jan, Hiscott, John, van Kuppeveld, Frank J. M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3997492/ https://www.ncbi.nlm.nih.gov/pubmed/24759703 http://dx.doi.org/10.1371/journal.pone.0095927 |
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