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Novel PPAR Pan Agonist, ZBH Ameliorates Hyperlipidemia and Insulin Resistance in High Fat Diet Induced Hyperlipidemic Hamster

Effective and safe pharmacological interventions for hyperlipidemia remains badly needed. By incorporating the key pharmacophore of fibrates into the natural scaffold of resveratrol, a novel structural compound ZBH was constructed. In present study, we found ZBH reserved approximately one third of t...

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Detalles Bibliográficos
Autores principales: Chen, Wei, Fan, Shiyong, Xie, Xinni, Xue, Nina, Jin, Xueyuan, Wang, Lili
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3997506/
https://www.ncbi.nlm.nih.gov/pubmed/24759758
http://dx.doi.org/10.1371/journal.pone.0096056