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Antiangiogenic Treatment Diminishes Renal Injury and Dysfunction via Regulation of Local AKT in Early Experimental Diabetes

In view of increased vascular endothelial growth factor-A (VEGF-A) expression and renal dysfunction in early diabetes, we designed a study to test whether VEGF-A inhibition can prevent early renal injury and dysfunction. We investigated the relationship and mechanism between VEGF-A and AKT regulatio...

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Detalles Bibliográficos
Autores principales: Bai, Xiaoyan, Li, Xiao, Tian, Jianwei, Zhou, Zhanmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3997561/
https://www.ncbi.nlm.nih.gov/pubmed/24759991
http://dx.doi.org/10.1371/journal.pone.0096117