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Tumor suppressor microRNA-34a inhibits cell proliferation by targeting Notch1 in renal cell carcinoma
MicroRNA-34a (miR-34a) is a tumor suppressive microRNA, which induces G1 arrest, apoptosis and senescence by repressing the expression of multiple oncogenes. This study aimed to investigate the biological function and molecular mechanisms of miR-34a in human renal cell carcinoma (RCC) cells. Quantit...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3997725/ https://www.ncbi.nlm.nih.gov/pubmed/24765202 http://dx.doi.org/10.3892/ol.2014.1931 |