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Tumor suppressor microRNA-34a inhibits cell proliferation by targeting Notch1 in renal cell carcinoma

MicroRNA-34a (miR-34a) is a tumor suppressive microRNA, which induces G1 arrest, apoptosis and senescence by repressing the expression of multiple oncogenes. This study aimed to investigate the biological function and molecular mechanisms of miR-34a in human renal cell carcinoma (RCC) cells. Quantit...

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Detalles Bibliográficos
Autores principales: ZHANG, CHANGCUN, MO, REN, YIN, BINDE, ZHOU, LIBIN, LIU, YONGCHAO, FAN, JIE
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3997725/
https://www.ncbi.nlm.nih.gov/pubmed/24765202
http://dx.doi.org/10.3892/ol.2014.1931