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Inhibition of cell growth by BrMC through inactivation of Akt in HER-2/neu-overexpressing breast cancer cells

We previously reported that chrysin (ChR) and its analogs induced cell cycle arrest and apoptosis in human estrogen receptor-positive/-negative breast cancer cells. However, it was unknown whether 8-bromo-7-methoxychrysin (BrMC), a novel synthetic ChR analog, inhibited the cell growth of human epide...

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Detalles Bibliográficos
Autores principales: CAO, XIAO-ZHENG, XIANG, HONG-LIN, QUAN, MEI-FANG, HE, LI-HUA
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3997727/
https://www.ncbi.nlm.nih.gov/pubmed/24765191
http://dx.doi.org/10.3892/ol.2014.1889