Population Pharmacokinetic Modelling of Recombinant Factor IX Fc Fusion Protein (rFIXFc) in Patients with Haemophilia B

BACKGROUND AND OBJECTIVES: Recombinant factor IX Fc fusion protein (rFIXFc) is a clotting factor developed using monomeric Fc fusion technology to prolong the circulating half-life of factor IX. The objective of this analysis was to elucidate the pharmacokinetic characteristics of rFIXFc in patients...

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Detalles Bibliográficos
Autores principales: Diao, Lei, Li, Shuanglian, Ludden, Thomas, Gobburu, Jogarao, Nestorov, Ivan, Jiang, Haiyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2014
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3997831/
https://www.ncbi.nlm.nih.gov/pubmed/24452809
http://dx.doi.org/10.1007/s40262-013-0129-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3997831/
https://www.ncbi.nlm.nih.gov/pubmed/24452809
http://dx.doi.org/10.1007/s40262-013-0129-7

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