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Population Pharmacokinetic Modelling of Recombinant Factor IX Fc Fusion Protein (rFIXFc) in Patients with Haemophilia B
BACKGROUND AND OBJECTIVES: Recombinant factor IX Fc fusion protein (rFIXFc) is a clotting factor developed using monomeric Fc fusion technology to prolong the circulating half-life of factor IX. The objective of this analysis was to elucidate the pharmacokinetic characteristics of rFIXFc in patients...
Autores principales: | Diao, Lei, Li, Shuanglian, Ludden, Thomas, Gobburu, Jogarao, Nestorov, Ivan, Jiang, Haiyan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3997831/ https://www.ncbi.nlm.nih.gov/pubmed/24452809 http://dx.doi.org/10.1007/s40262-013-0129-7 |
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