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Acid-mediated Lipinski’s second rule: application to drug design and targeting in cancer
With a predicted 382.4 per 100,000 people expected to suffer from some form of malignant neoplasm by 2015, and a current death toll of 1 out of 8 deaths worldwide, improving treatment and/or drug design is an essential focus of cancer research. Multi-drug resistance is the leading cause of chemother...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer Berlin Heidelberg
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3997836/ https://www.ncbi.nlm.nih.gov/pubmed/24687685 http://dx.doi.org/10.1007/s00249-014-0953-1 |