Vpx complementation of ‘non-macrophage tropic’ R5 viruses reveals robust entry of infectious HIV-1 cores into macrophages

BACKGROUND: It is now known that clinically derived viruses are most commonly R5 tropic with very low infectivity in macrophages. As these viruses utilize CD4 inefficiently, defective entry has been assumed to be the dominant restriction. The implication is that macrophages are not an important rese...

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Detalles Bibliográficos
Autores principales: Mlcochova, Petra, Watters, Sarah A, Towers, Greg J, Noursadeghi, Mahdad, Gupta, Ravindra K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3997928/
https://www.ncbi.nlm.nih.gov/pubmed/24656066
http://dx.doi.org/10.1186/1742-4690-11-25

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3997928/
https://www.ncbi.nlm.nih.gov/pubmed/24656066
http://dx.doi.org/10.1186/1742-4690-11-25

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