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The Relationship between the Antitumor Effect of the IL-12 Gene Therapy and the Expression of Th1 Cytokines in an HPV16-Positive Murine Tumor Model

Objective. The goal of the present study was to investigate the effect of IL-12 expressed in plasmid on the Th1 cytokine profile in an experimental HPV16-positive murine tumor model and the association with the IL-12's antitumor effect. Methods. Mice were injected with BMK-16/myc cells to estab...

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Detalles Bibliográficos
Autores principales: García Paz, Flor, Madrid Marina, Vicente, Morales Ortega, Ausencio, Santander González, Abimelec, Peralta Zaragoza, Oscar, Burguete García, Ana, Torres Poveda, Kirvis, Moreno, José, Alcocer González, Juan, Hernandez Marquez, Eva, Bermúdez Morales, Victor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3997981/
https://www.ncbi.nlm.nih.gov/pubmed/24808638
http://dx.doi.org/10.1155/2014/510846