Cargando…
The Relationship between the Antitumor Effect of the IL-12 Gene Therapy and the Expression of Th1 Cytokines in an HPV16-Positive Murine Tumor Model
Objective. The goal of the present study was to investigate the effect of IL-12 expressed in plasmid on the Th1 cytokine profile in an experimental HPV16-positive murine tumor model and the association with the IL-12's antitumor effect. Methods. Mice were injected with BMK-16/myc cells to estab...
Autores principales: | García Paz, Flor, Madrid Marina, Vicente, Morales Ortega, Ausencio, Santander González, Abimelec, Peralta Zaragoza, Oscar, Burguete García, Ana, Torres Poveda, Kirvis, Moreno, José, Alcocer González, Juan, Hernandez Marquez, Eva, Bermúdez Morales, Victor |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3997981/ https://www.ncbi.nlm.nih.gov/pubmed/24808638 http://dx.doi.org/10.1155/2014/510846 |
Ejemplares similares
-
In vivo Antitumor Effect of an HPV-specific Promoter driving IL-12 Expression in an HPV 16-positive Murine Model of Cervical Cancer
por: Bermúdez-Morales, Victor Hugo, et al.
Publicado: (2016) -
Bovine Interferon-Tau Activates Type I interferon-Associated Janus-signal Transducer in HPV16-positive Tumor Cell
por: Fierros-Zárate, Geny, et al.
Publicado: (2020) -
Interferon-Tau has Antiproliferative effects, Represses the Expression of E6 and E7 Oncogenes, Induces Apoptosis in Cell Lines Transformed with HPV16 and Inhibits Tumor Growth In Vivo
por: Padilla-Quirarte, Herbey Oswaldo, et al.
Publicado: (2016) -
Molecular Mechanism and Potential Targets for Blocking HPV-Induced Lesion Development
por: Guzmán-Olea, E., et al.
Publicado: (2012) -
Risk allelic load in Th2 and Th3 cytokines genes as biomarker of susceptibility to HPV-16 positive cervical cancer: a case control study
por: Torres-Poveda, K., et al.
Publicado: (2016)