Cargando…

The Relationship between the Antitumor Effect of the IL-12 Gene Therapy and the Expression of Th1 Cytokines in an HPV16-Positive Murine Tumor Model

Objective. The goal of the present study was to investigate the effect of IL-12 expressed in plasmid on the Th1 cytokine profile in an experimental HPV16-positive murine tumor model and the association with the IL-12's antitumor effect. Methods. Mice were injected with BMK-16/myc cells to estab...

Descripción completa

Detalles Bibliográficos
Autores principales:	García Paz, Flor, Madrid Marina, Vicente, Morales Ortega, Ausencio, Santander González, Abimelec, Peralta Zaragoza, Oscar, Burguete García, Ana, Torres Poveda, Kirvis, Moreno, José, Alcocer González, Juan, Hernandez Marquez, Eva, Bermúdez Morales, Victor
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3997981/ https://www.ncbi.nlm.nih.gov/pubmed/24808638 http://dx.doi.org/10.1155/2014/510846

Ejemplares similares

In vivo Antitumor Effect of an HPV-specific Promoter driving IL-12 Expression in an HPV 16-positive Murine Model of Cervical Cancer
por: Bermúdez-Morales, Victor Hugo, et al.
Publicado: (2016)

Bovine Interferon-Tau Activates Type I interferon-Associated Janus-signal Transducer in HPV16-positive Tumor Cell
por: Fierros-Zárate, Geny, et al.
Publicado: (2020)

Interferon-Tau has Antiproliferative effects, Represses the Expression of E6 and E7 Oncogenes, Induces Apoptosis in Cell Lines Transformed with HPV16 and Inhibits Tumor Growth In Vivo
por: Padilla-Quirarte, Herbey Oswaldo, et al.
Publicado: (2016)

Molecular Mechanism and Potential Targets for Blocking HPV-Induced Lesion Development
por: Guzmán-Olea, E., et al.
Publicado: (2012)

Risk allelic load in Th2 and Th3 cytokines genes as biomarker of susceptibility to HPV-16 positive cervical cancer: a case control study
por: Torres-Poveda, K., et al.
Publicado: (2016)

Relevance of miR-21 in regulation of tumor suppressor gene PTEN in human cervical cancer cells
por: Peralta-Zaragoza, Oscar, et al.
Publicado: (2016)

Lethality risk markers by sex and age-group for COVID-19 in Mexico: a cross-sectional study based on machine learning approach
por: Rojas-García, Mariano, et al.
Publicado: (2023)

The SNP at −592 of human IL-10 gene is associated with serum IL-10 levels and increased risk for human papillomavirus cervical lesion development
por: Torres-Poveda, Kirvis, et al.
Publicado: (2012)

Papel de las enfermedades infecciosas en el desarrollo de la esclerosis múltiple: evidencia científica
por: Bermúdez-Morales, Victor Hugo, et al.
Publicado: (2017)

RIPOR2 Expression Decreased by HPV-16 E6 and E7 Oncoproteins: An Opportunity in the Search for Prognostic Biomarkers in Cervical Cancer
por: Olmedo-Nieva, Leslie, et al.
Publicado: (2022)

Targeted treatments for cervical cancer: a review
por: Peralta-Zaragoza, Oscar, et al.
Publicado: (2012)

The Human Papillomavirus (HPV) E6 Oncoprotein Regulates CD40 Expression via the AT-Hook Transcription Factor AKNA
por: Manzo-Merino, Joaquin, et al.
Publicado: (2018)

Cervical Microbiome and Cytokine Profile at Various Stages of Cervical Cancer: A Pilot Study
por: Audirac-Chalifour, Astride, et al.
Publicado: (2016)

Cervical Cancer Genetic Susceptibility: A Systematic Review and Meta-Analyses of Recent Evidence
por: Martínez-Nava, Gabriela A., et al.
Publicado: (2016)

Prevalence and Risk Factors for High-Risk Human Papillomavirus Infection and Cervical Disorders: Baseline Findings From an Human Papillomavirus Cohort Study
por: Saldaña-Rodríguez, Paula, et al.
Publicado: (2023)

Polymorphisms in IL-10 and TGF-β gene promoter are associated with lower risk to gastric cancer in a Mexican population
por: Martínez-Campos, Cecilia, et al.
Publicado: (2019)

Critical Role of the Transcription Factor AKNA in T-Cell Activation: An Integrative Bioinformatics Approach
por: Ramírez-González, Abrahan, et al.
Publicado: (2023)

Los activos fijos de la gerencia regional de producción sureste de comisión federal de electricidad
por: González Campos, Ausencio Manuel
Publicado: (1999)

Functional Role of AKNA: A Scoping Review
por: Ramírez-González, Abrahán, et al.
Publicado: (2021)

Smartphone overuse, depression & anxiety in medical students during the COVID-19 pandemic
por: Santander-Hernández, Flor M., et al.
Publicado: (2022)

Human Papillomavirus-Related Recurrent Multiphenotypic Sinonasal Carcinoma With HPV Genotype 56 Detected by HPV Direct Flow CHIP
por: Remirez-Castellanos, Ana Lilia, et al.
Publicado: (2023)

Burden of disease and associated complications of hepatitis a in children and adults in Mexico: A retrospective database study
por: Guzman-Holst, Adriana, et al.
Publicado: (2022)

Correlation between mobility in mass transport and mortality due to COVID-19: A comparison of Mexico City, New York, and Madrid from a data science perspective
por: Vega-Villalobos, Andrea, et al.
Publicado: (2022)

HPV-Based Screening, Triage, Treatment, and Followup Strategies in the Management of Cervical Intraepithelial Neoplasia
por: Peralta-Zaragoza, Oscar, et al.
Publicado: (2013)

Mediation Analysis of Waist Circumference in the Association of Gut Microbiota with Insulin Resistance in Children
por: Ayala-García, Juan Carlos, et al.
Publicado: (2023)

A functional role of the SNP -592 of human IL10 gene regulatory region is associated with an increased IL-10 expression and risk for human papillomavirus cervical lesion and cervical cancer development
por: Torres-Poveda, K, et al.
Publicado: (2012)

Utility of MicroRNAs and siRNAs in Cervical Carcinogenesis
por: Díaz-González, Sacnite del Mar, et al.
Publicado: (2015)

The Autophagy Process in Cervical Carcinogenesis: Role of Non-Coding-RNAs, Molecular Mechanisms, and Therapeutic Targets
por: Lagunas-Martínez, Alfredo, et al.
Publicado: (2022)

High risk HPV infection prevalence and associated cofactors: a population-based study in female ISSSTE beneficiaries attending the HPV screening and early detection of cervical cancer program
por: Torres-Poveda, K., et al.
Publicado: (2019)

Interaction between Akkermansia muciniphila and Diet Is Associated with Proinflammatory Index in School-Aged Children
por: Ayala-García, Juan Carlos, et al.
Publicado: (2023)

Fas and Fas ligand are highly expressed in lymphocytes from cervical intraepithelial neoplasia and cervical cancer patients: A possible role for immune escaping
por: Contreras-Ochoa, Carla O., et al.
Publicado: (2022)

Barriers to adherence to cytology exam: a case study in low-income Colombian women
por: Bermúdez, Paula C., et al.
Publicado: (2023)

Quercetin induces G2 phase arrest and apoptosis with the activation of p53 in an E6 expression-independent manner in HPV-positive human cervical cancer-derived cells
por: Clemente-Soto, Aldo F., et al.
Publicado: (2019)

Antitumor Cannabinoid Chemotypes: Structural Insights
por: Morales, Paula, et al.
Publicado: (2019)

An Oncolytic Adenovirus Encoding SA-4-1BBL Adjuvant Fused to HPV-16 E7 Antigen Produces a Specific Antitumor Effect in a Cancer Mouse Model
por: Martinez-Perez, Alejandra G., et al.
Publicado: (2021)

Chlorido[2,3,5,6-tetrakis(tert-butylsulfanylmethyl)phenyl-κ(3) S (2),C (1),S (6)]palladium(II) dichloromethane monosolvate
por: Paz-Morales, Evelyn, et al.
Publicado: (2013)

Concomitant Antihyperalgesic and Antitumor Effects of Gabapentin in a Murine Cancer Pain Model
por: Brito, Beatriz Elena, et al.
Publicado: (2021)

Update on the Epidemiological Features and Clinical Implications of Human Papillomavirus Infection (HPV) and Human Immunodeficiency Virus (HIV) Coinfection
por: Pérez-González, Alexandre, et al.
Publicado: (2022)

Antitumor Effect of Bleomycin Nanoaerosol in Murine Carcinoma Model
por: Karshieva, Saida S., et al.
Publicado: (2023)

Treatment with Imiquimod enhances antitumor immunity induced by therapeutic HPV DNA vaccination
por: Chuang, Chi-Mu, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_j0968rn4sl3s34ostg0v10dl5u